12/20/2023 0 Comments How to use umod![]() ![]() ![]() To investigate whether rs12917707 associates with ESRD, graft failure (GF) and urinary uromodulin levels in an independent cohort, we genotyped 1142 ESRD patients receiving a renal transplantation and 1184 kidney donors as controls. The association of rs12917707 with end-stage renal disease (ESRD) in a recent case-control study was only nominally significant. In recent genetic association studies, common variants including rs12917707 in the UMOD locus have shown strong evidence of association with eGFR, prevalent and incident chronic kidney disease and uromodulin urinary concentration in general population cohorts.
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